FACULTY - SECONDARY FACULTY - ALAN TARTAKOFF

Alan Tartakoff, Ph.D.

Assistant Staff

Pathology Department
Cell Biology Program

Pathology Department:

1988

 Education:

Ph.D.: Cell Biology
Rockefeller University, 1973

Research:

Cell biology of the yeast nucleus during mitosis and karyogamy.
Cellular genomic methods development.
Huntington's Disease, Fragile X Syndrome.

  1. Morphogenesis of the nucleus of S. cerevisiae during the mitotic cell cycle
  2. Mechanism of nuclear fusion and genome encounters during karyogamy in S. cerevisiae
  3. Development of novel microarray-based methods to identify single genes responsible for cellular phenotypes (animal cells and yeast)
  4. Molecular correction of inherited defects in Huntington's Disease and in the Fragile X Syndrome

Selected Publications

Nanduri, J. and Tartakoff, A.
The Arrest of Secretion Response: Signaling via Wsc proteins and Pkc1p Relocates Yeast Nuclear Proteins to the Cytoplasm.
Molecular Cell 8, 281-289 (2001). /

Gabel, L., Won S., Kawai, H., McKinney, M., Tartakoff, A. and Fallon, J.
Visual Experience Regulates Transient Expression and Dendritic Localization of Fragile X Mental Retardation Protein.
J. Neuroscience 24, 10579-10583 (2004). /

Liu, Y., Guo, D., Tartakoff, P. and Tartakoff, A.
A Crm1p-independent nuclear export path for the mRNA-associated protein, Npl3p/Mtr13p.
PNAS 96, 6739- 6744 (1999). /

Kadowaki, T., Chen, S., Hitomi, M., Jacobs, E., Kumagai, C., Liang, S., Schneiter, R., Singleton, D., Wisniewska, J. and Tartakoff, A. M.
Isolation of S. cerevisiae mRNA Transport-Defective Mutants.
Cell Biol. 126, 649-659 (1994). /