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PRIMARY AND SECONDARY FACULTY |
Primary and Secondary Faculty
In addition to faculty holding primary appointments in the Center, the Center
includes faculty from several departments within the Medical School (Biochemistry,
Genetics , Pathology, Molecular Biology and Microbiology, and Medicine) as well as several
researchers from the Cleveland Clinic.
| Primary Faculty | Research | Primary Affiliation |
| Kristian Baker | Mechanism of nonsense-mediated mRNA decay in Saccharomyces cerevisiae | RNA Center |
| James P. Bruzik | Regulation of alternative pre-mRNA splicing | RNA Center |
| Mark G. Caprara | Catalytic RNAs, RNPs and mitochondrial gene expression | RNA Center |
| Jeff Coller | Translational Control and mRNA Decay | RNA Center |
| Pieter deHaseth | Transcription initiation by bacterial RNA polymerase | RNA Center |
| Jonatha Gott | Mechanistic studies of RNA Editing in Physarum mitochondria | RNA Center |
| Michael E. Harris | Molecular recognition and catalysis by the ribonuclease P: A ribonucleoprotein enzyme. Analysis of phosphoryl transfer mechanisms using kinetic isotope effects. |
RNA Center |
| Timothy W. Nilsen Director |
Mechanisms of post transcriptional gene regulation | RNA Center |
| Saba Valadkhan | Functional analysis of the spliceosome | RNA Center |
| Secondary Faculty | Research | Primary Affiliation |
| Erik D. Andrulis | RNA surveillance mechanisms in yeast and flies | Department of
Molecular Biology & Microbiology Case Western Reserve University |
| Kwaku Dayie | Structure, Dynamics, and Thermodynamics of RNA, RNA-RNA, RNA- protein interactions using Biomolecular NMR spectroscopy | Department of Molecular Biology Cleveland Clinic Foundation |
| Donna M. Driscoll | Mechanisms of posttranscriptional gene regulation: RNA editing and translational recoding of UGA as selenocysteine | Cell Biology Department Lerner Research Institute, Cleveland Clinic |
| Maria Hatzoglou | Gene Regulation Mechanisms during physiological Stress | Department of Nutrition Case Western Reserve University |
| Eckhard Jankowsky | Molecular Mechanism of RNA helicases | Dept. of Biochemistry Case Western Reserve University |
| Andrea Ladd | Pre-mRNA alternative splicing regulation in vertebrate heart and muscle | Department of Cell Biology Cleveland Clinic Foundation |
| Hua Lou | Regulation of pre-mRNA processing in neurons and cancer cells | Department of Genetics Case Western Reserve University |
| A. Gregory Matera | Molecular genetics of small RNP biogenesis | Department of Genetics Case Western Reserve University |
| David McPheeters | mRNA splicing in S.cerevisiae | Department of Molecular Biology and Microbiology Case Western Reserve University |
| Richard A. Padgett | Mechanism of pre-mRNA splicing | Cleveland Clinic Foundation |
| Helen Salz | Regulation of alternative splicing during Drosophila development | Department of Genetics Case Western Reserve University |
| Alan Tartakoff | Cell biology of the yeast nucleus during mitosis and karyogamy. Cellular genomic methods development. Huntington's Disease, Fragile X Syndrome. | Pathology Department/Cell Biology Program Case Western Reserve University |
| Michael Weiss | Control of gene expression and protein folding | Department of Biochemistry Case Western Reserve University |
| Jo Ann Wise | Mechanism and regulation of RNA splicing in S.pombe | Department of Molecular Biology and Microbiology Case Western Reserve University |


