PRIMARY AND SECONDARY FACULTY

Primary and Secondary Faculty

In addition to faculty holding primary appointments in the Center, the Center includes faculty from several departments within the Medical School (Biochemistry, Genetics , Pathology, Molecular Biology and Microbiology, and Medicine) as well as several researchers from the Cleveland Clinic.
Primary Faculty Research Primary Affiliation
Kristian Baker Mechanism of nonsense-mediated mRNA decay in Saccharomyces cerevisiae RNA Center
James P. Bruzik Regulation of alternative pre-mRNA splicing RNA Center
Mark G. Caprara Catalytic RNAs, RNPs and mitochondrial gene expression RNA Center
Jeff Coller Translational Control and mRNA Decay RNA Center
Pieter deHaseth Transcription initiation by bacterial RNA polymerase RNA Center
Jonatha Gott Mechanistic studies of RNA Editing in Physarum mitochondria RNA Center
Michael E. Harris Molecular recognition and catalysis by the ribonuclease P: A ribonucleoprotein enzyme.
Analysis of phosphoryl transfer mechanisms using kinetic isotope effects.
RNA Center
Timothy W. Nilsen
Director
Mechanisms of post transcriptional gene regulation RNA Center
Saba Valadkhan Functional analysis of the spliceosome RNA Center
Secondary Faculty Research Primary Affiliation
Erik D. Andrulis RNA surveillance mechanisms in yeast and flies Department of Molecular Biology & Microbiology
Case Western Reserve University
Kwaku Dayie Structure, Dynamics, and Thermodynamics of RNA, RNA-RNA, RNA- protein interactions using Biomolecular NMR spectroscopy Department of Molecular Biology
Cleveland Clinic Foundation
Donna M. Driscoll Mechanisms of posttranscriptional gene regulation: RNA editing and translational recoding of UGA as selenocysteine Cell Biology Department
Lerner Research Institute, Cleveland Clinic
Maria Hatzoglou Gene Regulation Mechanisms during physiological Stress Department of Nutrition
Case Western Reserve University
Eckhard Jankowsky Molecular Mechanism of RNA helicases Dept. of Biochemistry
Case Western Reserve University
Andrea Ladd Pre-mRNA alternative splicing regulation in vertebrate heart and muscle Department of Cell Biology
Cleveland Clinic Foundation
Hua Lou Regulation of pre-mRNA processing in neurons and cancer cells Department of Genetics
Case Western Reserve University
A. Gregory Matera Molecular genetics of small RNP biogenesis Department of Genetics
Case Western Reserve University
David McPheeters mRNA splicing in S.cerevisiae Department of Molecular Biology and Microbiology
Case Western Reserve University
Richard A. Padgett Mechanism of pre-mRNA splicing Cleveland Clinic Foundation
Helen Salz Regulation of alternative splicing during Drosophila development Department of Genetics
Case Western Reserve University
Alan Tartakoff Cell biology of the yeast nucleus during mitosis and karyogamy. Cellular genomic methods development. Huntington's Disease, Fragile X Syndrome. Pathology Department/Cell Biology Program
Case Western Reserve University
Michael Weiss Control of gene expression and protein folding Department of Biochemistry
Case Western Reserve University
Jo Ann Wise Mechanism and regulation of RNA splicing in S.pombe Department of Molecular Biology and Microbiology
Case Western Reserve University