Mark G. Caprara, Ph.D.

Assistant Professor

Center for RNA Molecular Biology

Complete Publication List

Downing, M.E., Brady, K.L. and Caprara M.G. (2005).
A C-terminal fragment of an intron-encoded maturase is sufficient for promoting group I intron splicing.
RNA, 11, 437-446. /

Fernandez, J., Yaman, I., Huang, C., Liu, H., Lopez, A.B., Komar, A.A. Caprara, M.G., Merrick, W.C., Snider, M.D., Kaufman, R.J., Lamers, W.H. and Hatzoglou, M. (2005)
Ribosome Stalling Regulates IRES-Mediated Translation in Eukaryotes, a Parallel to Prokaryotic Attenuation.
Mol. Cell, 17, 405-416. /

Caprara M.G. and Waring, R.B. (2005)
Group I Introns and their maturases: Uninvited, but welcome guests.
in “Homing Endonucleases and Inteins” eds. M. Belfort, V. Derbyshire, B.L. Stoddard, and D. Wood. Springer-Verlag.

Bolduc, J.M., Spiegel, P.C., Chatterjee, P., Brady, K.L., Downing, M.E., Caprara M.G., Waring, R.B., and Stoddard B.L. (2003).
Structural and biochemical analyses of DNA and RNA binding by a bifunctional homing endonuclease and group I intron splicing factor.
Genes Dev., 17, 2875-2888. /

Chatterjee. P., Brady, K.L., Solem, A., Ho, Y., Caprara, M.G. (2003).
Functionally distinct nucleic acid binding sites for a group I intron encoded RNA maturase/DNA homing endonuclease.
J. Mol Biol., 329, 239-251.

Yaman, I., Fernandez, J., Liu, H., Caprara, M., Komar, A.A., Koromilas, A.E., Zhou, L., Snider, M.D., Scheuner, D., Kaufman, R.J. and Hatzoglou, M. (2003).
The zipper model of translational control: a small upstream ORF is the switch that controls structural remodeling of an mRNA leader.
Cell, 113, 519-531.

Solem, A., Chatterjee, P. and Caprara, M.G. (2002)
A novel mechanism for protein-assisted group I intron splicing.
RNA, 8, 412-425. /

Caprara, M.G., Myers, C.A. and Lambowitz, A.M. (2001).
Interaction of the Neurospora crassa mitochondrial tyrosyl-tRNA synthetase (CYT-18 protein) with the group I intron P4-P6 domain. Thermodynamic analysis and the role of metal ions.
J Mol Biol., 308, 165-190.

Caprara M.G. and Nilsen, T.W. (2000).
RNA: Versatility in form and function.
Nat Struct Biol.,7, 831-833.

Lambowitz, A.M., Caprara, M.G., Zimmerly S. and Perlman, P.S. (1999).
Group I and group II ribozymes as RNPs: clues to the past and guides to the future.
in “The RNA World II”, (eds. R.F.Gesteland, J.F. Atkins and T.R. Cech), pp. 451-485. Cold Spring Harbor Laboratory Press, New York.

Wallweber, G.J., Mohr, S., Rennard, R., Caprara, M.G. and Lambowitz, A.M. (1997).
Characterization of Neurospora mitochondrial group I introns reveals different CYT-18 dependent and independent splicing strategies and an alternative 3' splice site for an intron ORF.
RNA, 3, 114-131.

Caprara, M.G., Lehnert, V., Lambowitz, A.M. and Westhof, E. (1996).
A tyrosyl-tRNA synthetase recognizes a conserved tRNA-like structural motif in the group I intron catalytic core.
Cell, 87, 1135-1145.

Myers, C.A., Wallweber, G.J., Rennard, R., Kemel, Y., Caprara, M.G., Mohr, G. and Lambowitz, A.M. (1996).
A tyrosyl-tRNA synthetase suppresses structural defects in the two major helical domains of the group I intron catalytic core.
J. Mol. Biol., 262, 87-104.

Caprara M.G., Mohr, G. and Lambowitz, A.M. (1996).
A tyrosyl-tRNA synthetase protein induces tertiary folding of the group I intron catalytic core.
J. Mol. Biol., 257, 512-531.

Mohr, G., Caprara, M.G., Guo, Q. and Lambowitz, A.M. (1994).
A tyrosyl-tRNA synthetase can function similarly to an RNA structure in the Tetrahymena ribozyme.
Nature, 370, 147-150.

Caprara M.G. and Waring, R.B. (1994).
Deletion of P9 and stem-loop structures downstream from the catalytic core affects both 5' and 3' splicing activities in a group I intron.
Gene, 143, 29-37.

Caprara, M.G. and Waring, R.B. (1993).
Important 2'-hydroxyl groups in the core of a group I intron.
Biochemistry, 32, 3604-3610.